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What is Remeron?

Remeron (mirtazapine) is a tetracyclic antidepressant. It affects chemicals in the brain that may become unbalanced and cause depression. It is thought to increase the activity of norepinephrine and serotonin which help elevate mood. Remeron is used to treat major depressive disorder. 

 

http://clinicaltrials.gov/show/NCT00302107

 

Study of Mirtazapine for Post-Traumatic Stress Disorder (PTSD) in Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) Veterans and Veterans From All Other Southwest Conditions

 

Exclusion Criteria:

  • Lifetime history of bipolar I, psychotic, or cognitive disorders

  • Actively suicidal, homicidal, or psychotic

  • History of sensitivity to mirtazapine

  • Unstable general medical conditions

  • Score 6 on Question #10 of MADRS regarding suicidal ideation

  • Women who are pregnant, planning to become pregnant or breastfeed during the study

 

Keywords provided by Department of Veterans Affairs:

Mirtazapine                                                       PTSD
Veterans                                                           antidepressant


Additional relevant MeSH terms:

Anxiety Disorders                                               Stress Disorders, Post-Traumatic
Stress Disorders, Traumatic                               Mental Disorders
Mirtazapine                                                          Mianserin
Antidepressive Agents, Tricyclic                        Antidepressive Agents
Psychotropic Drugs                                             Central Nervous System Agents
Therapeutic Uses                                                Pharmacologic Actions

Histamine H1 Antagonists                                   Histamine Antagonists
Histamine Agents                                                Neurotransmitter Agents
Physiological Effects of Drugs                            Adrenergic alpha-Antagonists
Adrenergic Antagonists                                      Adrenergic Agents
Serotonin Antagonists                                        Serotonin Agents
Antidepressive Agents, Second-Generation

Molecular Mechanisms of Pharmacological Action

 

ClinicalTrials.gov processed this record on June 25, 2014

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